Ketamine therapy has emerged as a groundbreaking treatment for mental health conditions tike treatment resistant depression, anxiety, and PTSD. However, the delivery method can significantly impact the experience and outcomes. Let’s explore the key differences between IV and oral ketamine therapy to help you navigate your options.

Efficacy: Speed and high efficacy vs. Convenience and moderate efficacy

• IV Ketamine: Delivers the medication directly into the bloodstream, bypassing the digestive system. This results in rapid onset of action, often within hours. IV ketamine is known for its high bioavailability, meaning a larger percentage of the drug reaches the brain. In clinic therapy allows the doctor administering the drug to adjust the infusion to meet individual challenges and immediately treat side effects.
• Oral Ketamine: Absorbed through the digestive system, leading to a slower onset of action, typically within days or weeks. Bioavailability is lower compared to IV, requiring higher doses to achieve similar effects. The medication is reported to taste bad, and such high doses are required to start to get effective therapy that side effects are also encountered.

Side Effects: Intensity vs. Manageability

• IV Ketamine: Can induce more intense but short-lived side effects like dissociation, dizziness, altered perception, and nausea. These effects are closely monitored by medical professionals during the infusion and can be treated immediately.
• Oral Ketamine: Generally associated with milder and more manageable side effects like nausea ,dizziness, dissociation or drowsiness. These effects are often experienced at home, requiring careful monitoring and support.

Integration Therapy: Essential for Lasting Change

Regardless of the delivery method, integration therapy is crucial for maximizing the benefits of ketamine therapy. It involves working with a therapist to process the experiences and insights gained during treatment, fostering lasting behavioral changes and emotional growth.

Choosing Your Path

The optimal delivery method depends on individual needs, preferences, and medical history. lV ketamine may be preferred for those seeking rapid relief or with treatment-resistant conditions. Oral ketamine offers a more convenient but somewhat less effective option for individuals who prefer this approach.

Consult with a qualified healthcare professional to determine the best ketamine therapy approach for your unique circumstances.